

Professional depigmentation method for resistant pigmentation

cosmelan® is a pioneering depigmentation method developed by Mesoestetic®, a global leader in pigmentation management. The system targets visible pigmentation and the underlying cellular mechanisms responsible for melanin overproduction. It is...
recognised for its efficacy in treating severe and resistant pigmentation across all skin types. The method integrates a professional application with a multi‑month home protocol to maintain continuous depigmenting activity. cosmelan® uses an innovative formula containing a patented molecule and encapsulated active complex to regulate melanin synthesis. Clinical outcomes show progressive improvement from the first weeks, with sustained clarity and uniformity over time. The system is widely used for melasma, sun‑induced spots, post‑inflammatory pigmentation, and uneven tone.
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Used by more than one million patients worldwide. Recognised by professionals for treating resistant pigmentation. Suitable for diverse skin types and phototypes.
Formulated with a patented molecule and an encapsulated active complex. Targets melanin synthesis and cellular dysregulation. Delivers a comprehensive approach to pigment control.
Demonstrates strong results in melasma, sun damage, and PIH. Effective for severe and recurrent pigmentation. Validated through extensive clinical use.
Visible improvement begins within the first weeks. Maintains skin uniformity and clarity over time. Reduces recurrence through continuous regulation.
Combines professional application with structured home maintenance. Acts on visible pigment and the root cause of overproduction. Supports stable, long‑lasting outcomes.
Includes professional treatment, home pack, and Cosmelan® 2 cream. Allows tailored protocols based on severity and skin type. Supports ongoing maintenance after the professional method.