

Medical depigmentation method for long‑term pigment regulation

Dermamelan® is developed by Mesoestetic®, a global reference in depigmentation with more than 30 years of research and clinical experience. The method targets both visible pigmentation and the underlying cellular mechanisms responsible for melanin...
overproduction. It is recognised for its efficacy across diverse pigmentation types and skin tones. The treatment begins with an in‑clinic application of two intensive depigmenting masks, followed by a four‑month home protocol to maintain continuous pigment regulation. Dermamelan® is suitable for all Fitzpatrick skin types and is widely used for melasma, sun damage, acne‑related pigmentation, and uneven tone. Clinical outcomes show progressive improvement from the first weeks, with sustained uniformity and clarity over time.
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This phase includes the application of two intensive depigmenting masks designed to target accumulated pigment and initiate regulation. The treatment is performed following a clinical assessment to ensure suitability and optimize results.
This phase follows a structured four month protocol using complementary products to maintain continuous depigmenting activity. It helps regulate melanin overproduction and supports long term stability of skin tone.
Formulated with proprietary technologies protected by two patents. Targets melanin synthesis and cellular dysregulation. Delivers a unique mechanism of action for long‑term pigment control.
Demonstrates strong results in melasma, sun damage, and PIH. Effective on resistant and recurrent pigmentation. Validated across diverse Fitzpatrick skin types.
Visible improvement begins within the first weeks. Maintains skin uniformity and clarity over time. Reduces recurrence through continuous regulation.
Includes professional treatment, home pack, and maintenance cream. Allows tailored protocols based on severity and skin type. Supports ongoing regulation after the in‑clinic phase.




